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Tuesday, March 5, 2019

Friabililty Test of Mefenamic Acid Tablets

One of the shielding criteria of mechanical strength of birth control pills tablet crumbliness testing. Tablets must be able to withstand mechanical stresses during their manufacturing, distribution and intervention by the end-user. During the process of coating, transportation, packing and processing tablet, tablet will dawdle some weight. Because of that, the friability test is performed in the pharmaceutical in disseminatery to test the tendency of a tablet breaking into smaller pieces during transit.It includes repeatedly falling a sample of tablets over a fixed time by using friability tester and then checking whether any tablets ar broken, and enumerate the percentage of loss weight of tablets. A good compressed tablet should not loss more than 1% of its weight. Based on this experiment, by and by the operation ended, the weight loss of tablets is 0. 0395g which is equivalent to 0. 68% loss from its weight. This means, those tablets atomic number 18 good role and str ong tablets which then can endure the stresses.There are maybe some error during handling the experiment that can bakshish to incorrect results. After operation ended, the tablets are not fully cleaned from dust which is affect the result. When finished, the samples have to be de-dusted first before weigh again. final result The percentage loss of weight of samples is 0. 68%. The samples are good quality tablets because the percentage loss of weight are not more than 1%. 1. http//en. wikipedia. org/wiki/Friability 2. http//www. anabiotec. com/testing/detail/hardness-friability-disintegration

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